The Strongest CBD Topicals for Deep-Seated Pain Relief

Looking for some deep-seated relief? Here are the top nine strongest CBD creams, lotions, and balms on the market today.

Written by

Mell Green

Mell is a cannabis connoisseur who has been published in nearly 50 online publications surrounding cannabis, including Cannabis Industry Association, Analytical Cannabis, Terpenes and Testing Magazine, Plant People, Byrdie, and...

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Strong CBD topical balm for pain relief
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CBD is a cannabinoid that’s packed full of all sorts of benefits — including pain relief. With anti-inflammatory and analgesic properties, CBD offers a great option for people who suffer from stubborn aches and pains.

Topicals like CBD creams are one of the best products to use to help with either pain relief or help with skin complications like dryness or redness, as they’re easy to apply and provide concentrated, targeted effects in the areas that need it most. And we’ve got a list of the top eight strongest CBD topicals to choose from. 

These high-potency CBD formulas are going to be ideal for those with mild to moderate pain issues. If you need something stronger for chronic pain, opt for a dispensary-grade THC-rich cannabis topical. But, if you do not have access to cannabis products in your state, then these strong hemp-derived CBD creams will be the next most powerful options.

We analyzed 70 brands and tested 15 popular CBD topicals, ranging from $30 to $140, to find the strongest options for targeted pain relief. (See how we test.)

8 Strongest CBD Topicals

Here are our top picks for the most potent CBD creams, lotions, and balms for targeted pain relief and reducing inflammation.

BrandPotency (mg)Price
Game Up9,200$69.99
Extract Labs2,000$89.99
Martha Stewart7,500$99
Aspen Green1,000$84.99
Level Select1,800$49.99
Hometown Hero1,000$60

Neurogan CBD Cooling Cream

Neurogan’s 16,000 mg CBD cream is easily one of the most potent topicals you’ll ever apply. 

Potent CBD cream for pain relief
Photo: Neurogan

Available for $124.95 from Neurogan

When it comes to high-potency, powerful formulas for aches and pains, Neurogan and their 16,000 mg full-spectrum cream have you covered. This CBD cooling rub is highly rated and for good reason: many people find this topical easy to apply and they love how quickly the powerful effects kick in.

At 16,000 mg, even the most stubborn aches and pains can subside and you can feel a bit of relief. This well-made topical comes in two refreshing scents, too: Orange & Lemon, as well as Rosemary & Lavender. 

Read our full Neurogan review

Pros & Cons


  • High-potency full-spectrum formula
  • Potent enough for even the most experienced consumers 
  • Extremely well priced
  • Works beautifully to reduce deep-seated aches and pains
  • Helps hydrate the skin, leaving it feeling soft and velvety
  • Cruelty-free and gluten-free
  • Comprehensive third-party lab results for potency and purity (view COA)


  • No fragrance-free options 
  • No THC-free options for those who need it 
  • Slightly thin, watery texture
  • Packaging and labeling could be higher quality
  • Ingredients are not certified organic

Game Up Power Balm

Game Up’s 9,200 mg Power Balm is not only incredibly potent, but it has the best application, too.

Super strength CBD cream for athletes
Photo: Game Up

Available for $69.99 from Game Up

You’ll never complain about rubbing some of Game Up Nutrition’s Power Balm on your achy and sore muscles. This CBD balm smells delicious and is made of organic ingredients like cannabidiol, beeswax, and coconut oil, as well as a bit of menthol, too.

This balm applies on the body beautifully, not leaving behind any weird residue or texture. The formula absorbs quickly, and you don’t have to worry about it rubbing off on your clothes or staining. In general, this balm is ideal for post-workout recovery, as it helps with sore, aching muscles and joints nearly immediately.  

Pros & Cons


  • Ultra high-potency CBD balm 
  • Applies beautifully and quickly blends into the skin
  • Smells nice and light; not overpowering 
  • Good for those who don’t want THC 
  • Great for post-workouts and achy, sore muscles
  • Ideal for lowering inflammation


  • Made with CBD isolate; no other cannabinoids or terpenes 
  • No full-spectrum options
  • No other strength options 
  • Needs to be reapplied frequently for results to continue
  • Not third-party tested for contaminants (view COA)

Extract Labs CBD Muscle Cream

Extract Lab’s full-spectrum muscle cream is one of the most potent on the market because of its strong blend of THC and CBD.

Organic CBD muscle cream
Photo: Extract Labs

Available for $89.99 from Extract Labs

Inside Extract Lab’s full-spectrum Muscle Cream is 2,000 mg of CBD and 100 mg of THC. Together, this creates a super-strong formula that is perfect for reducing inflammation, lowering pain levels, and even helping with sleep at night.

This muscle cream penetrates deep into the muscles, allowing for targeted, concentrated relief that absolutely everyone deserves. Easily applied, this cream goes great in any bag as your go-to topical product, whether you’re at the gym, work, or school. 

Read our full Extract Labs review

Pros & Cons


  • Strong blend of 2000 mg CBD and 100 mg THC
  • Full-spectrum formula allows for fuller, more prominent relief 
  • Great for reducing strong aches and pains
  • Helpful for those with arthritis 
  • Helps lower inflammation and swelling 
  • Hundreds of five-star reviews
  • USDA-certified organic
  • Made with only eight natural ingredients
  • Ships internationally and offers a 60-day money-back guarantee
  • Fully lab tested for potency and contaminants (view COA)


  • Cream is slightly greasy 
  • Menthol addition is very strong; may be overpowering to some
  • Expensive for the size of the product
  • No non-THC options for those who want it

Martha Stewart Super-Strength CBD Cream

Even Martha Stewart herself has a high-potency, strong CBD cream for your aching joints to enjoy.

High strength CBD cream for pain
Photo: Martha Stewart CBD

Available for $99 from Martha Stewart CBD

The Super Strength CBD cream from Martha Stewart is packed full of 7,500 mg of broad-spectrum CBD extract for your aching, sore muscles to enjoy. Not only that, but buyers also enjoy the hydrating, soothing properties that this super-strength cream brings.

In general, though, I felt that this cream was best for reducing muscle discomfort and muscle stiffness, so if you’re having trouble not feeling as mobile as you once did, this CBD cream may be a great option. 

Read our full Martha Stewart CBD review

Pros & Cons


  • High-potency broad-spectrum CBD cream option
  • Great for reducing muscle soreness and stiffness
  • Good for improving mobility 
  • Helps hydrate and soothe the skin
  • Smells amazing; not overpowering or artificial 
  • Made with a cruelty-free formula
  • Lab tested for potency and purity (view COA)


  • Contains various unnatural ingredients 
  • Few customer reviews on their website
  • Not as potent as some consumers may need 
  • No full-spectrum options available

cbdMD Freeze Roller

cbdMD’s Freeze Roller topical is the perfect option for easy, no-mess application and a whole lot of pain relief. 

CBD freeze roller product for athletes
Photo: cbdMD

Available for $79.99 from cbdMD

The Freeze Roller from cbdMD is the perfect CBD topical for those who don’t want to deal with any messy residue or cream. This topical rolls onto your skin flawlessly, as it comes with a massaging roller ball attached that dispenses the topical as you roll.

At 3,000 mg of broad-spectrum extract, this topical is quite potent, and may work well for those with arthritis pains, especially in the hands and wrists. You can take this topical with you anywhere you go, as it will never make a mess and you can apply it instantly with no hassle.

Read our full cbdMD review

Pros & Cons


  • Available in various strengths, including a hefty 3,000 mg option
  • Affordably priced at $0.03/mg
  • Easy, no-mess application 
  • Great for on-the-go use 
  • Helpful for intense aches and pains, especially in hard-to-reach areas
  • Hundreds of five-star reviews
  • Lab tested for potency and contaminants


  • Not a cream option for those who prefer it 
  • Cooling element is very strong; may be overpowering for some
  • Contains various non-organic ingredients 
  • No THC options for those who want it

Aspen Green Muscle Relief Cooling Cream

Aspen Green’s Muscle Relief Cooling Cream is made specifically to help ease the aches and pains in your muscles, giving you a soothing, cooling experience. 

High strength CBD cream with cooling formula
Photo: Aspen Green

Available for $84.99 from Aspen Green

Inside Aspen Green’s Muscle Relief Cooling Cream is 1,000 mg of full-spectrum CBD extract, used specifically to provide well-rounded, powerful effects when applied. This topical is made with 100% natural, food-grade ingredients and is free of plasticizers, artificial preservatives, and synthetic ingredients.

Aspen Green even uses a purified water-based formula for easy, better application and quick absorption. Altogether, you’ll be pleasantly surprised by the amount of pain relief and relaxation that this CBD cream can bring, even with one of the lowest mg amounts on the list. (Just goes to show that numbers aren’t everything!) 

Read our full Aspen Green review

Pros & Cons


  • Uses a potent full-spectrum formula for better results 
  • Helps to relieve deep-seated aches and pains, as well as workout knots 
  • Gentle cooling sensation that’s great for non-sensitive areas
  • Toxin-free, cruelty-free, and free of synthetic ingredients 
  • Easy to apply 
  • Water-based formula makes for quick absorption
  • High quality packaging and container
  • USDA-certified organic
  • Extracted from organic hemp grown in Colorado
  • Fully lab tested for potency and purity (view COA)


  • One of the pricier topicals on this list at $84.99 for 1,000 mg
  • Only one strength option available 
  • No THC-free option 
  • Effects fade quickly and re-application is necessary

Level Select Sports CBD Cream

If you’re an athlete looking to experience some enhanced workout recovery, Level Select’s CBD Sports Cream may be the right choice for you.

CBD sports cream for athletes
Photo: Level Select

Available for $49.99 from Level Select

Level Select offers their high-quality CBD Sports Cream in three different strengths: 900 mg, 1,200 mg, or 1,800 mg depending on how strong of topical you need. The 1,800 mg option is great for those who suffer from severe pain and discomfort within the muscles and joints, as the formula is strong and incredibly fast-acting. In fact, Level Select uses nano-technology to shrink CBD cannabinoids, increasing their bioavailability and making it quicker and easier for your body to absorb the goodness. 

Pros & Cons


  • Made in three different strengths
  • Affordably priced at just $49.99 for 1,800 mg
  • Great for post-workout recovery
  • Ideal for lowering pain and inflammation in muscles and joints 
  • Good for hydrating and soothing the skin 
  • Non-greasy and fast-absorbing
  • Fully lab tested for potency and contaminants such as pesticides, heavy metals, and solvents (view COA)


  • No THC options 
  • No fragrance-free options 
  • Mint scent is very strong and slightly off-putting 
  • Relief is not long-lasting
  • Ingredients are not organic; some are not natural

Hometown Hero Delta-8 THC Roll-On

Hometown Hero’s delta-8 THC roll-on may not be primarily CBD, but it sure does help with pain relief and muscle relaxation. 

Delta-8 THC roller for pain relief
Photo: Hometown Hero

Available for $60 from Hometown Hero

Okay, we know: this isn’t a CBD topical. But, it is a super powerful cannabinoid topical that’s wonderful for those looking for enhanced pain relief.

This roll-on includes 1,000 mg of delta-8 THC paired with menthol to create a cooling, relaxing result. Hometown Hero’s delta-8 Roll-On works quickly and doesn’t make any sort of mess when applied. And, even though delta-8 is technically psychoactive, you don’t have to worry about experiencing psychoactive effects because of the topical application. Instead, you just get enhanced, powerful relief that’s quite different from your typical CBD experience. 

Read our full Hometown Hero review

Pros & Cons


  • Includes 1,000 mg of delta-8 THC
  • Delta-8 creates powerful, unique pain relief and relaxation 
  • Easy to apply; no-mess application
  • Nice cooling feature that isn’t too powerful
  • Nearly instant relief 
  • Donates a portion of each sale to a veteran-based charity
  • Fully lab tested for potency and contaminants such as pesticides, heavy metals, and solvents (view COA)


  • No CBD option
  • Not good for those wanting to avoid THC 
  • Not available in every state
  • Not as potent as some of the stronger CBD options on this list

How We Tested the CBD Topicals

Quality testing various CBD topical creams for pain relief
We analyzed and tested the strongest CBD topicals on the market to determine the most effective options for targeted pain relief. Photo: Mell Green / CBD Oracle

Curating this list of the top eight strongest CBD creams and balms wasn’t something that we took lightly. In order for us to come up with these results, we had to first look at all the top brands and their CBD topical options. Then, we analyzed these products using strict criteria to see how they held up among each other in certain categories. 

We rated them in these categories on a scale of 1-10, then averaged their scores. If a brand didn’t score at least a 7.5, then it didn’t make our list. Thus, we were left with our top products. From there, we ranked them solely based on overall potency and strength. 

Testing the effectiveness of a CBD topical for pain relief
We thoroughly tested each product to ensure effectiveness for common pain relief needs. Photo: Mell Green / CBD Oracle

In case you want to know the criteria we used to analyze these products, we’ve written them out for you down below: 

  • Lab Results: Does the brand have lab results readily available? Are they updated and come from accredited labs? Are they full-panel or standard-panel? 
  • Potency: How potent is the CBD topical (mg/ml)? What are the milligrams? Did they use full-spectrum, broad-spectrum, or CBD isolate?
  • Effectiveness: How effective was the cream for pain relief? Did it reduce pain significantly or only a little? How long did the pain relief last? How long did it take to kick in? 
  • Price: What is the price per milligram? Is the cream affordable or expensive? Is it worth its price point? 
  • Formulation: What did the brand use to make the topical? Were the ingredients organic and natural? What kind of extract was used? Do any of the ingredients have the potential for harm?

Learn more about how we test products.

Finding the Strongest CBD Topical for You

When it comes to finding the strongest hemp CBD topicals, it’s important to note that each topical works differently for every person. Thus, you can’t just pay attention to numbers (milligrams). Sometimes, you may find that a full-spectrum 3,000 mg CBD cream is more helpful than a 10,000 mg CBD isolate cream. It simply depends on what works best for you and your body. 

So, the next time you’re feeling uncomfortable, sore, and in need of a bit of pain relief, try turning to one of the super-strong CBD creams on this list. These topicals are designed to help you feel better, whether it be reducing back pain, helping with arthritis, or even just lowering discomfort enough to fall asleep at night. You just have to find the perfect option for you — thankfully, you’ve got eight incredible options right here to choose from.

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